Venlafaxine reduces hot flashes in hormone receptor-positive breast cancer patients receiving tamoxifen: a prospective single-arm, open-label trial

Key Points

• Hot flashes significantly decreased with venlafaxine among patients in the trial, indicating effective symptom relief.
• Patients experienced a notable reduction of over 50% in hot flash frequency after treatment with venlafaxine.
• This was a prospective single-arm trial assessing the impact of venlafaxine on women undergoing tamoxifen therapy.
• These findings highlight the potential of venlafaxine as an effective intervention for managing hot flashes during tamoxifen treatment.