Esculetin alleviates IgA nephropathy in rats by improving intestinal mucosal function through the IL-17/NF-κB signaling

Key Points

• Esculetin alleviates igA nephropathy, improving renal function and intestinal health.
• Key evidence reveals a significant reduction in kidney inflammation and damage in treated rats.
• Analysis of intestinal mucosal function highlights a role for il-17 and nf-kb signaling pathways.
• This work suggests promising therapeutic potential for esculetin in managing igA nephropathy.