Overlapping autoimmunity and demyelination syndromes associated with TNF inhibitor therapy

Key Points

• Autoimmunity and demyelination syndromes occur with TNF inhibitor therapy, hinting at overlapping disease mechanisms.
• A notable connection was identified, as these syndromes may arise concurrently in treatment, emphasizing the need for vigilance.
• Assessment involved examining clinical cases to illustrate the pathophysiology behind these phenomena and their clinical implications.
• Awareness of these potential syndromes alongside TNF inhibitor therapy may inform clinical practice and patient management.