Molecular insights, challenges and progressions of polysaccharide and protein-based biopolymeric carriers for intranasal drug delivery: A review

Key Points

• Biopolymeric carriers enhance intranasal drug delivery efficacy, leading to improved therapeutic outcomes.
• Intranasal delivery showed significant advantages, including rapid absorption and bypass of the blood-brain barrier.
• This review analyzes various polysaccharide and protein carrier systems, focusing on their molecular insights and applications.
• Challenges such as stability and immunogenicity of these carriers are discussed, highlighting the need for continued research.