Koenigia mollis, an underexplored traditional medicinal plant (MP) from Nagaland, was investigated for its phytochemical composition with emphasis on characterisation of bioactive constituents. Metabolic profiling was conducted using preliminary phytochemical screening, Fourier Transform Infra-red Spectroscopy (FT-IR) and Gas Chromatography-Mass Spectrometry (GC-MS). GC-MS enabled tentative identification of 45 phytochemical (PC) compounds through spectral comparison with reference databases, while FT-IR analysis revealed functional groups supporting structural elucidation. Preliminary screening confirmed the presence of major phytochemical classes such as alkaloids, flavonoids, terpenoids etc. In silico tools were employed where screened compounds exhibited pharmacokinetic properties, drug-likeness and potential biological activities of identified compounds. This study highlights the chemical diversity of Koenigia mollis and provides foundational phytochemical data, contributing valuable insights to the limited knowledge of underexplored medicinal plants and underscoring its medicinal potential.
Kuotsu et al. (Sun,) studied this question.