No Effect of a Single Session of Anodal Transcranial Direct Current Stimulation on Exercise-Induced Hypoalgesia in Knee Osteoarthritis: A Randomized Cross-Over Trial

Key Points

• To assess the impact of anodal transcranial direct current stimulation on exercise-induced pain relief in knee osteoarthritis.
• Conducted as a randomized cross-over trial
• Participants underwent two sessions with and without stimulation
• Measured pain responses after exercise
• No significant difference in pain reduction was found between stimulation and non-stimulation sessions
• Exercise did not enhance pain relief during the stimulation period