Surface Modification of Intraocular Lens with Zwitterionic Poly(Carboxybetaine) for Posterior Capsular Opacification Prevention

Key Points

• The study aims to explore the effectiveness of zwitterionic poly(carboxybetaine) in preventing posterior capsular opacification on intraocular lenses.
• Evaluated surface modification techniques on intraocular lenses.
• Assessed the adhesion and proliferation of lens epithelial cells on modified lenses.
• Conducted comparative analyses of treated versus untreated lenses.
• Zwitterionic modification significantly reduced LEC adhesion on the IOL surface.
• The treatment showed a decrease in the proliferation of LECs compared to control lenses.
• Surface-modified lenses displayed enhanced biocompatibility.