Bone-Targeted Calcification–Photothermal Nanoplatform for Synergistic Tumor Ablation and Bone Regeneration in Breast Cancer Bone Metastasis

Key Points

• The aim is to develop a nanoplatform that simultaneously ablates tumors and promotes bone regeneration in breast cancer bone metastasis.
• Developed a bone-targeted calcification-photothermal nanoplatform
• Tested efficacy in tumor ablation and bone regeneration models
• Analyzed outcomes using imaging and histological techniques
• The nanoplatform significantly reduced tumor size
• Improved bone regeneration was observed post-treatment
• Enhanced overall therapeutic efficacy compared to traditional approaches