What question did this study set out to answer?

The aim is to highlight the metastatic nature of invasive lobular carcinoma and the challenges in its detection.

March 10, 2026Journal of Medical Case Reports1 citationsOpen Access

Invasive lobular carcinoma of the breast with multifocal gastrointestinal, ovarian, and peritoneal metastases: a case report

NKNeda KarkeabadiMotamed Cancer Institute RORamesh OmranipourMotamed Cancer Institute ANAysan NozhehIran University of Medical Sciences

Key Points

The aim is to highlight the metastatic nature of invasive lobular carcinoma and the challenges in its detection.
Reported a case of invasive lobular carcinoma with multiple metastases.
Evaluated symptoms and tumor markers in relation to gastrointestinal and ovarian issues.
Discussed limitations of conventional imaging techniques.
Identified gastrointestinal and ovarian metastases that were missed by standard imaging.
Noted the importance of monitoring tumor markers in patients with a history of invasive lobular carcinoma.
Emphasized the need for early histopathological evaluation in symptomatic patients.

Abstract

This case highlights the insidious metastatic behavior of invasive lobular carcinoma and the limitations of conventional imaging in detecting gastrointestinal and ovarian involvement. Persistent or unexplained gastrointestinal symptoms and rising tumor markers in patients with a history of invasive lobular carcinoma should prompt consideration of metastatic disease and early histopathological evaluation.

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