This meta-analysis aims to evaluate the efficacy and safety of mazdutide in managing overweight and obesity among non-diabetic adults.
Conducted a meta-analysis of randomised controlled trials (RCTs)
Analyzed weight, waist circumference, and blood pressure outcomes
Assessed the incidence of adverse events associated with mazdutide
Mazdutide significantly reduces weight and waist circumference
Improves blood pressure in the studied population
Potential mild to moderate adverse events were observed, though limited by trial numbers
Abstract
Mazdutide effectively reduces weight, waist circumference and blood pressure but may cause mild to moderate adverse events. Findings are limited by the small number of RCTs.