Efficacy and Safety of Mazdutide in Managing Overweight and Obesity Among Non-Diabetic Adults: A Meta-Analysis of Randomised Controlled Trials.

Key Points

• This meta-analysis aims to evaluate the efficacy and safety of mazdutide in managing overweight and obesity among non-diabetic adults.
• Conducted a meta-analysis of randomised controlled trials (RCTs)
• Analyzed weight, waist circumference, and blood pressure outcomes
• Assessed the incidence of adverse events associated with mazdutide
• Mazdutide significantly reduces weight and waist circumference
• Improves blood pressure in the studied population
• Potential mild to moderate adverse events were observed, though limited by trial numbers