Electrogenetic modulation of glutamate receptor neurons following deep brain stimulation of the nucleus accumbens

Key Points

• To investigate how deep brain stimulation (DBS) of the nucleus accumbens (NAc) affects glutamate receptor neurons through electrogenetic modulation.
• Utilized deep brain stimulation on nucleus accumbens in mouse models.
• Collected stereo-seq data to analyze neuronal responses.
• Examined the modulation of glutamate receptors post-stimulation.
• Observed significant changes in glutamate receptor activity following DBS.
• Identified patterns in the electrogenetic alterations in the nucleus accumbens neurons.