Direct C-H magnesiation of thiophenes with a Mg-Mg-bonded compound

Key Points

• To explore an efficient approach for C-H magnesiation of thiophenes using a Mg-Mg-bonded compound.
• Utilized a Mg-Mg-bonded compound in the reaction with thiophenes.
• Conducted ortho C-H magnesiation process.
• Observed the release of hydrogen gas (H2) during the reaction.
• Successfully formed magnesium thienyl complexes from thiophene substrates.
• Demonstrated efficient reaction conditions with minimal by-product formation.