Fmoc-Phe : Fmoc-Leu supramolecular hydrogels with adaptive antibacterial activity

Key Points

• The research aims to explore the mechanical properties and antibacterial activity of dual-component Fmoc-Phe and Fmoc-Leu hydrogels.
• Developed dual-component hydrogels using Fmoc-Phe and Fmoc-Leu.
• Assessed mechanical properties and thermoresponsiveness.
• Evaluated antibacterial activity against Gram-positive and Gram-negative bacteria by varying the component ratios.
• Hydrogels exhibited tunable mechanical properties based on composition.
• Antibacterial activity varied significantly with adjustments to the building-block ratio, effective against both Gram-positive and Gram-negative pathogens.