What question did this study set out to answer?

This research aims to investigate the repeatability of flow-mediated dilation in children with chronic inflammatory disease compared to healthy peers.

March 15, 2026Clinical Physiology and Functional Imaging0 citationsOpen Access

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Brachial artery flow‐mediated dilation is less repeatable in children with a chronic inflammatory disease compared to their healthy peers

MBMadelyn M. ByraMcMaster University NPNicole A. ProudfootMcMaster University KCKatharine D. CurrieMichigan State University

Key Points

This research aims to investigate the repeatability of flow-mediated dilation in children with chronic inflammatory disease compared to healthy peers.
Measured flow-mediated dilation in children with chronic inflammatory disease and healthy peers.
Analyzed coefficient of variation for relative flow-mediated dilation.
Assessed repeatability of measurements over time.
Flow-mediated dilation showed a large coefficient of variation in children with chronic inflammatory disease.
Less repeatability was observed in children with chronic inflammatory disease compared to healthy peers.

Abstract

FMD is less repeatable in children with a CID, and our findings of a large CV for relative FMD suggest that measurement error could be a challenge to reliably tracking changes in FMD over time in this paediatric population.

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Brachial artery flow‐mediated dilation is less repeatable in children with a chronic inflammatory disease compared to their healthy peers

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Abstract

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