PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 15, 2026Surgical Case Reports0 citationsOpen Access

Two Cases of Intraductal Papilloma with Sebaceous Metaplasia of the Breast

KOKurumi OkadaTTTakashi TashiroTOT. Okuno

Key Points

  • This research describes the rare occurrence of sebaceous metaplasia in benign intraductal papillomas.
  • Detailed histological examination of surgically resected breast tissue
  • Analysis of imaging findings preceding surgery
  • Case reporting of two individual patients
  • Both cases were histologically confirmed as benign
  • Sebaceous metaplasia was identified, marking a rare presentation
  • Imaging results initially suggested possible malignancy

Abstract

INTRODUCTION: Intraductal papilloma is a common benign breast lesion that typically presents with nipple discharge or a palpable mass. While apocrine metaplasia is frequently observed, sebaceous metaplasia is very rare in breast lesions, with only a few cases reported to date. We herein describe two surgically resected cases of intraductal papilloma with sebaceous metaplasia, both of which were histologically proven benign following imaging findings that were suspicious for malignancy.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Okada et al. (2026) studied this question.

synapsesocial.com/papers/69b64d48b42794e3e660e04dhttps://doi.org/10.70352/scrj.cr.25-0658
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An Intraductal Papilloma Mimicking Malignancy in the Breast2026
  2. 2Giant Intraductal Papilloma of Breast2024
  3. 3A Case of Squamous Cell Carcinoma Arising From an Intraductal Papilloma of the Breast2025
  4. 4Concurrent intraductal papilloma and nipple adenoma: a case report and review of the literature2026
  5. 5A Rare Case of Mucinous Carcinoma Arising in Association with an Intraductal Papilloma2026 · 1 citations