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March 15, 2026Surgical Case Reports0 citationsOpen Access

Two Cases of Intraductal Papilloma with Sebaceous Metaplasia of the Breast

KOKurumi OkadaTTTakashi TashiroTOT. Okuno

Key Points

  • This research describes the rare occurrence of sebaceous metaplasia in benign intraductal papillomas.
  • Detailed histological examination of surgically resected breast tissue
  • Analysis of imaging findings preceding surgery
  • Case reporting of two individual patients
  • Both cases were histologically confirmed as benign
  • Sebaceous metaplasia was identified, marking a rare presentation
  • Imaging results initially suggested possible malignancy

Abstract

INTRODUCTION: Intraductal papilloma is a common benign breast lesion that typically presents with nipple discharge or a palpable mass. While apocrine metaplasia is frequently observed, sebaceous metaplasia is very rare in breast lesions, with only a few cases reported to date. We herein describe two surgically resected cases of intraductal papilloma with sebaceous metaplasia, both of which were histologically proven benign following imaging findings that were suspicious for malignancy.

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Cite This Study

Okada et al. (2026) studied this question.

synapsesocial.com/papers/69b64d48b42794e3e660e04dhttps://doi.org/10.70352/scrj.cr.25-0658
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