Case study reveals mucinous carcinoma associated with intraductal papilloma, highlighting risk factors.
INTRODUCTION: Intraductal papilloma (IDP) is a benign breast lesion that accounts for 3%–6% of core biopsy diagnoses. It is considered a high-risk precursor due to its association with atypia, ductal carcinoma in situ, and invasive carcinoma. Although IDP-NOS (not otherwise specified) rarely progresses to invasive cancer, IDP with atypia carries a higher risk of malignant transformation.
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Yamasaki et al. (2026) studied this question.
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