Concurrent intraductal papilloma and nipple adenoma: a case report and review of the literature

Nipple adenoma is a rare benign proliferative lesion that makes up <1% of diagnosed benign breast lesions. The diagnosis of an intraductal papilloma is more common and represents an estimated 2%–3% of all benign breast tumours. The concomitant diagnoses of these pathologies together is extremely rare. Here, we report the case of a 34-year-old female that presented with a left-sided nipple lesion discovered on self-exam. Subsequent imaging was classified as BIRADS 4A and the patient opted to undergo surgical excision. Resultant pathology revealed both nipple duct adenoma and intraductal papilloma with florid ductal hyperplasia and focal atypia. Given the rarity of underlying nipple pathologies and the associated diagnostic difficulties, a thorough and complete workup is crucial even when benign breast pathology is suspected.