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March 16, 2026Anatolian Current Medical Journal0 citations

The albumin–bilirubin score can reflect disease severity in alcohol-associated hepatitis and cirrhosis

MSMusa SalmanoğluSBSüleyman BaşYAYasemin Kaldirim Armutcuoglu

Key Points

  • The study aims to assess the clinical relevance of the albumin-bilirubin score in alcohol-associated liver diseases, specifically hepatitis and cirrhosis.
  • Retrospective case control design
  • Included 51 patients with alcohol-associated hepatitis, 39 with cirrhosis, and 48 healthy controls
  • Calculated albumin-bilirubin score for all participants
  • Recorded Child-Pugh classification for cirrhosis patients and Maddrey’s Discriminant Function for hepatitis patients
  • Calculated MELD-Na score and Fibrosis-4 index for all participants.
  • Mean ALBI scores were highest in the alcohol-associated hepatitis patients
  • Mean ALBI scores were lowest in the healthy controls
  • Statistical significance was noted in the differences in ALBI scores among groups.

Abstract

Aims: The albumin-bilirubin (ALBI) score has been evaluated in various liver diseases, however its clinical relevance in alcoholassociated liver disease (ALD) remains unclear. This study aimed to evaluate whether the ALBI score reflects disease severity in patients with alcohol-associated hepatitis (AH) and alcohol-associated cirrhosis (AC).Methods: In this retrospective case control study, 51 AH patients, 39 AC patients, and 48 healthy controls (HCs) were included. The ALBI score was calculated for all participants. The Child-Pugh classification (CPC A-C) was recorded for AC, while Maddrey’s Discriminant Function (MDF) for AH. The Model for End-Stage Liver Disease Sodium (MELD-Na) score was calculated for both patient groups, and the Fibrosis-4 (FIB-4) index was calculated in all participants. Results: Mean ALBI scores were highest in the AH patients and the lowest in the HCs (p

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Cite This Study

Salmanoğlu et al. (2026) studied this question.

synapsesocial.com/papers/69b79e398166e15b153ab46ehttps://doi.org/10.38053/acmj.1848023
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ALBI and Child-Pugh Score in Predicting Mortality in Chronic Liver Disease Patients Secondary to Alcohol: A Retrospective Comparative Study2026
  2. 2Albumin-bilirubin score reflects the extent of liver fibrosis in chronic hepatitis C patients treated with direct-acting antivirals2025
  3. 3Association between albumin–bilirubin score, model for end-stage liver disease score, platelet–albumin–bilirubin score, and acute-on-chronic liver failure complications: a cross-sectional study in a Chinese population2026
  4. 4Comparative Analysis of Albumin-Bilirubin (ALBI) Score and Child-Pugh Score for Prognostic Stratification in Hepatocellular Carcinoma Patients: A Single-Center Experience From North India2026
  5. 5Albumin-Bilirubin Score as A Predictor of Mortality in Patients with Hepatocellular Carcinoma2025