Left atrial reservoir strain, conduit strain, and circularity independently predict recurrent stroke and new-onset atrial fibrillation in patients with embolic stroke of undetermined source.
Do left atrial sphericity and strain augment risk prediction for recurrent stroke and new atrial fibrillation in patients with Embolic Stroke of Undetermined Source?
Left atrial strain and circularity serve as non-invasive markers of atrial cardiomyopathy that can help risk-stratify patients with ESUS for recurrent stroke and new atrial fibrillation.
LA reservoir and conduit strain, and circularity have independent and incremental association with occurrence of recurrent-stroke and new-AF in ESUS patients. This may represent measurable non-invasive markers of atrial cardiomyopathy in a subset of ESUS patients, and enable risk-stratification, and targeted intervention. Future longitudinal studies are needed to confirm these findings.
Clark et al. (2026) studied this question. Left atrial reservoir strain, conduit strain, and circularity independently predict recurrent stroke and new-onset atrial fibrillation in patients with embolic stroke of undetermined source.