What question did this study set out to answer?

This research investigates how cumulative low-density lipoprotein cholesterol (LDL-C) levels affect the risk of end-stage renal disease (ESRD) in patients with type 2 diabetes.

March 19, 2026Journal of Diabetes Investigation0 citationsOpen Access

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Risk of end‐stage renal disease in Korean patients with type 2 diabetes according to cumulative low‐density lipoprotein cholesterol levels

DLDa‐Yeon LeeKangbuk Samsung Hospital KHKyung‐Do HanSoongsil University JKJi‐Hee Ko

Key Points

This research investigates how cumulative low-density lipoprotein cholesterol (LDL-C) levels affect the risk of end-stage renal disease (ESRD) in patients with type 2 diabetes.
Analyzed the relationship between cumulative LDL-C levels and ESRD risk
Focused on Korean patients with type 2 diabetes
Considered factors like duration of diabetes and number of antidiabetic medications
Found a higher risk of ESRD with increasing cumulative LDL-C levels
Notably higher risk was observed in patients taking multiple antidiabetic medications
Longer duration of diabetes was associated with a greater impact of LDL-C on ESRD risk

Abstract

ESRD risk increased with high cumulative LDL-C levels. This difference was more pronounced in patients with diabetes taking multiple antidiabetic medications and in those with a longer duration of diabetes.

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Cite This Study

Lee et al. (Mon,) studied this question.

synapsesocial.com/papers/69bb929b496e729e629800e2 https://doi.org/https://doi.org/10.1111/jdi.70282

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