What question did this study set out to answer?

This research aims to assess the clinical outcomes related to mortality and hospitalization among patients with mitral valve prolapse under 65 years of age.

March 21, 2026Journal of the American Heart Association0 citationsOpen Access

Mortality, Hospitalization, and Cardiac Interventions Among Patients With Mitral Valve Prolapse <65 Years of Age

Q: What are the key findings of this study?

Mitral valve prolapse in patients under 65 years of age is associated with appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

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ABAditya BhonsaleElectrophysiology JZJonathan ZawadzkiUniversity of Pittsburgh FTFloyd ThomaUniversity of Pittsburgh

Key Result

Mitral valve prolapse in patients under 65 years of age is associated with appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

Key Points

This research aims to assess the clinical outcomes related to mortality and hospitalization among patients with mitral valve prolapse under 65 years of age.
Analyzed a large real-world cohort of patients under 65 years with mitral valve prolapse.
Examined clinical and echocardiographic profiles based on age and MVP subtype.
Identified substantial morbidity and mortality associated with mitral valve prolapse.
Noted variations in clinical outcomes depending on age at presentation and MVP subtype.

Structured PICO

Population

Patients <65 years of age with mitral valve prolapse (MVP)

Outcome

Mortality, hospitalization, and cardiac interventionshard clinical

Patients under 65 with mitral valve prolapse experience appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

Abstract

In a large contemporary real-world cohort of patients <65 years of age with MVP, the clinical and echocardiographic profile varies by age at presentation and MVP subtype with appreciable morbidity and mortality.

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Cite This Study

Bhonsale et al. (2026) studied this question. Mitral valve prolapse in patients under 65 years of age is associated with appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

synapsesocial.com/papers/69be35d76e48c4981c67447b https://doi.org/10.1161/jaha.125.046241

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March 21, 2026Journal of the American Heart Association0 citationsOpen Access

Mortality, Hospitalization, and Cardiac Interventions Among Patients With Mitral Valve Prolapse <65 Years of Age

View Full Paper

ABAditya BhonsaleElectrophysiology JZJonathan ZawadzkiUniversity of Pittsburgh FTFloyd ThomaUniversity of Pittsburgh

Key Result

Mitral valve prolapse in patients under 65 years of age is associated with appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

Key Points

This research aims to assess the clinical outcomes related to mortality and hospitalization among patients with mitral valve prolapse under 65 years of age.
Analyzed a large real-world cohort of patients under 65 years with mitral valve prolapse.
Examined clinical and echocardiographic profiles based on age and MVP subtype.
Identified substantial morbidity and mortality associated with mitral valve prolapse.
Noted variations in clinical outcomes depending on age at presentation and MVP subtype.

Structured PICO

Population

Patients <65 years of age with mitral valve prolapse (MVP)

Outcome

Mortality, hospitalization, and cardiac interventionshard clinical

Patients under 65 with mitral valve prolapse experience appreciable morbidity and mortality, with clinical and echocardiographic profiles varying by age and subtype.

Abstract

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View Full Paper

Cite This Study

synapsesocial.com/papers/69be35d76e48c4981c67447b https://doi.org/10.1161/jaha.125.046241

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View Full Paper