Molecular epidemiological characterization of invasive extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from infants less than 3 months old in East Asia | Synapse
March 22, 2026Open Access
Molecular epidemiological characterization of invasive extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from infants less than 3 months old in East Asia
Key Points
The research aims to characterize the molecular epidemiology of antibiotic-resistant E. coli and K. pneumoniae in infants.
Analyzed isolates from infants less than 3 months old in East Asia.
Measured ceftriaxone resistance levels in bacterial samples.
Identified predominant sequence types such as ST1193 and ST131.
Ceftriaxone resistance was found in approximately 30% of isolates from Taiwan and over 60% from Korea.
E. coli ST1193 and ST131 were the predominant strains identified.
Abstract
E. coli and K. pneumoniae are major Gram-negative pathogens in neonatal sepsis. Ceftriaxone resistance was detected in ~30% of isolates in Taiwan and >60% in Korea. E. coli ST1193 and ST131 predominated