Predictors of SARS-CoV-2 anti-Spike IgG antibody levels following two COVID-19 vaccine doses among children and adults in the Canadian CHILD Cohort

Key Points

• The research aims to identify factors that influence antibody responses following COVID-19 vaccination in various age groups.
• Analyzed data from the Canadian CHILD Cohort
• Assessed factors like prior infection, age, and vaccine type
• Measured anti-Spike IgG antibody levels in vaccinated individuals
• Prior SARS-CoV-2 infection significantly influenced antibody levels
• Younger and older age groups showed different antibody responses
• Vaccine type impacted post-vaccination antibody development