Transplacental therapy guided by echocardiographic diagnosis achieved complete rhythm control in 74% and partial rhythm control in 24% of fetuses with sustained supraventricular tachycardia.
Observational (n=32)
No
Does transplacental therapy guided by echocardiographic diagnosis improve rhythm control in fetuses with sustained supraventricular tachycardia?
Transplacental therapy guided by fetal echocardiography is highly effective for managing fetal sustained supraventricular tachycardia, achieving complete or partial rhythm control in 98% of cases.
Fetal echocardiography plays a pivotal role in the diagnosis and management of fetal arrhythmias, allowing evaluation of the electrophysiological mechanism and guiding appropriate medical therapy. Herein, we describe our ten-year experience as a tertiary referral center in Southern Italy in the diagnosis and management of fetal sustained supraventricular tachycardia. Thirty-two consecutive fetuses were included: 16 fetuses with atrioventricular reentrant tachycardia, 7 fetuses with ectopic atrial tachycardia, 8 fetuses with atrial flutter, and 1 fetus with permanent junctional reciprocating tachycardia. Transplacental therapy guided by echocardiographic diagnosis was highly effective in achieving complete rhythm control (74%) or partial rhythm control (24%), even in presence of heart failure or hydrops fetalis. Postnatal antiarrhythmic therapy was not required in over one third of cases due to spontaneous resolution. Earlier gestational age at diagnosis was associated with arrhythmia resolution at birth. The presence of fetal heart failure or hydrops did not predict postnatal persistence of arrhythmia.
Ciriello et al. (Sun,) conducted a observational in Fetal sustained supraventricular tachycardia (n=32). Transplacental therapy guided by echocardiographic diagnosis was evaluated on Complete rhythm control. Transplacental therapy guided by echocardiographic diagnosis achieved complete rhythm control in 74% and partial rhythm control in 24% of fetuses with sustained supraventricular tachycardia.