The addition of atezolizumab to mFOLFOX6 significantly improved disease-free survival among patients with stage III dMMR colon cancer. (Funded by the National Cancer Institute of the National Institutes of Health and Genentech; ATOMIC ClinicalTrials.gov number, NCT02912559.).
“Further investigation into the combined cardiotoxicity profile of ICI and FOLFOX therapies will help improve cardiovascular surveillance and management of these patients.”
Sinicrope et al. (Wed,) studied this question.