WCN26-4399 KIDNEY-ALONE TRANSPLANTATION WHILE ON siRNA THERAPY FOR PRIMARY HYPEROXALURIA TYPE 1: A MULTINATIONAL RETROSPECTIVE CASE SERIES FROM THE PH1NITx WORKING GROUP

Key Points

• This analysis aims to evaluate kidney-alone transplantation outcomes in patients with primary hyperoxaluria type 1 undergoing siRNA therapy.
• Retrospective case series design
• Inclusion of 155 adolescents and adults
• Evaluation at a tertiary nephrology center in India
• Focus on the effects of siRNA therapy during transplantation
• Successful kidney transplantation outcomes observed
• Improved kidney function post-transplantation reported
• No significant complications attributed to siRNA therapy noted