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March 28, 2026Journal of Pharmacy and Pharmacology0 citations

Capilliposide from Lysimachia capillipes Hemsl. shows anti-inflammatory and anti-pyretic effects via the MAPK/iNOS/NF- κ B pathway

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FXFanwei XiaJZJunyu ZhangDLDongbiao Lu

Key Points

  • To evaluate the anti-inflammatory and anti-pyretic effects of capilliposide from Lysimachia capillipes through specific molecular pathways.
  • In vitro experiments to assess anti-inflammatory effects
  • In vivo experiments to evaluate anti-pyretic effects
  • Analysis of the MAPK/iNOS/NF-κB signaling pathway involved in these effects
  • Capilliposide showed significant anti-inflammatory effects both in vivo and in vitro
  • The compound effectively reduced fever in animal models
  • Mechanistic studies confirmed involvement of the MAPK/iNOS/NF-κB pathway

Abstract

In summary, our results demonstrated that LC exhibited excellent anti-inflammatory and anti-pyretic effects in vivo and in vitro through MAPK/inducible nitric oxide synthase/NF-κB pathway.

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Cite This Study

Xia et al. (2026) studied this question.

synapsesocial.com/papers/69c772158bbfbc51511e25c7https://doi.org/10.1093/jpp/rgag021
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