What question did this study set out to answer?

To evaluate the anti-inflammatory and anti-pyretic effects of capilliposide from Lysimachia capillipes through specific molecular pathways.

March 28, 2026

Capilliposide from Lysimachia capillipes Hemsl. shows anti-inflammatory and anti-pyretic effects via the MAPK/iNOS/NF- κ B pathway

Key Points

To evaluate the anti-inflammatory and anti-pyretic effects of capilliposide from Lysimachia capillipes through specific molecular pathways.
In vitro experiments to assess anti-inflammatory effects
In vivo experiments to evaluate anti-pyretic effects
Analysis of the MAPK/iNOS/NF-κB signaling pathway involved in these effects
Capilliposide showed significant anti-inflammatory effects both in vivo and in vitro
The compound effectively reduced fever in animal models
Mechanistic studies confirmed involvement of the MAPK/iNOS/NF-κB pathway

Abstract

In summary, our results demonstrated that LC exhibited excellent anti-inflammatory and anti-pyretic effects in vivo and in vitro through MAPK/inducible nitric oxide synthase/NF-κB pathway.

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