From benign to malignant: Spectrum of skeletal muscle tumors in pediatric patients – A case series

Objectives: To demonstrate the biological spectrum of pediatric skeletal muscle tumors by presenting cases of fetal-type rhabdomyoma and embryonal rhabdomyosarcoma. Methods: Two pediatric cases were evaluated using clinical examination, imaging modalities, histopathology, and immunohistochemistry. Diagnostic findings and disease progression patterns were analyzed. Results: Fetal-type rhabdomyoma exhibited slow growth and benign behavior, while embryonal rhabdomyosarcoma demonstrated aggressive local invasion and systemic involvement. Both cases highlighted distinct biological characteristics despite overlapping clinical presentations. Conclusions: Accurate differentiation between benign and malignant skeletal muscle tumors is essential for optimal management. Multidisciplinary diagnostic approaches improve early detection and treatment planning.