Use of Latency Models to Assess the Association between Use of Topical Corticosteroids (CS) and Incident Cataract among Eyes of Patients with Uveitis

Key Points

• The aim is to evaluate how the use of topical corticosteroids correlates with the development of cataracts in uveitis patients.
• Analyzed associations between topical corticosteroid use and incident cataract occurrences
• Utilized latency models to examine the relationship during varying disease activity periods
• Focused on eyes of patients diagnosed with uveitis
• Topical corticosteroid use significantly increases cataract risk during inactive or borderline disease activity
• No increased risk observed during clearcut disease activity periods
• Potential protective effects of corticosteroids during inflammation may explain differing outcomes