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The study explores the link between amino acid metabolism in the gut-liver axis and intestinal extracellular matrix remodeling in weaned piglets.

April 1, 2026Animal Nutriomics0 citationsOpen Access

Integrated metabolomics and proteomics insights into the association of enhanced gut-liver axis amino acids metabolism with remodeling intestinal extracellular matrix in weaned piglets

YHYiyi HeGuizhou University QTQingsong TangMinistry of Agriculture WXWentuo XuMinistry of Agriculture

Key Points

The study explores the link between amino acid metabolism in the gut-liver axis and intestinal extracellular matrix remodeling in weaned piglets.
Random division of 96 weaned piglets into control and antibiotics groups.
Intervention with antibiotics for 14 days.
Measurement of average daily gain (ADG) as an outcome.
Antibiotics increased the average daily gain (ADG) in weaned piglets.

Abstract

Specialized physiological structures within the intestinal mucosa may participate in regulating amino acid metabolism along the gut-liver axis.To achieve this, a total of 96 weaned piglets were randomly divided into the control group and the antibiotics group, for 14 days.The results showed that antibiotics increased the average daily gain (ADG) and

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