Microbial dysbiosis has been recognized as a critical factor in the development of lung cancer, but most current research has focused on the gut rather than the lung microbiota. Identifying the key microbes involved in the development of lung adenocarcinoma is therefore essential. In this study, we analyzed the composition and structure of the microbiota in early-stage lung adenocarcinoma tissues in comparison to noncancerous lung tissues. Our findings provide novel insights into the diagnostic potential of the lung microbiota in early-stage lung adenocarcinoma and enhance our understanding of its involvement in tumor progression and the discovery of potential therapeutic targets.
Sun et al. (Mon,) studied this question.