Preoperative Beta‐Hydroxy‐Beta‐Methyl‐Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice

Key Points

• To investigate the effects of preoperative HMB supplementation on hepatic mitochondrial function after partial hepatectomy.
• Conducted a preoperative intervention with HMB supplementation in mice.
• Performed partial hepatectomy to assess liver recovery.
• Measured mitochondrial dynamics proteins and function post-surgery.
• HMB supplementation reduced levels of mitochondrial dynamics proteins.
• Preserved mitochondrial capacity following partial hepatectomy.