Trends toward earlier age at menarche, the starting point in women’s reproductive lifespan, have been observed globally. Whether an earlier age at menarche influences Anti-Müllerian hormone (AMH), a clinical indicator of ovarian reserve, remains unclear due to a lack of community-based data. This nationwide cross-sectional survey was carried out in China’s 15 provinces from May 2019 to April 2021, utilizing a multistage stratified sampling method to ensure sample representativeness and containing a total of 8 278 women aged 21–49 years. Self-reported age at menarche acts as exposure. Participants were categorized as age at menarche 4.0 µIU/ml. Our results support the opinion that women with early age at menarche in a community-based population have lower AMH level. Periodic AMH monitoring are necessary in children/adolescents with an early age at menarche. For individuals with early age at menarche, they should consider the optimal timing for childbearing.
Lou et al. (Mon,) studied this question.