Purpose To compare the difference, correlation, and agreement of anterior chamber parameters measured by Pentacam and CASIA 2. Methods A total of 89 myopic patients (89 right eyes) of Beijing Tongren Hospital were included. Anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) were measured by Pentacam and CASIA 2, respectively. Paired t ‐test, Pearson correlation analysis, and Bland–Altman analysis were used to evaluate the differences, correlation, and agreement between measurements. Results There were no significant differences in ACD or ACV between the two devices ( p > 0.05), whereas ACA values were significantly larger with CASIA 2 in all quadrants ( p < 0.001). ACD and ACV demonstrated strong correlations ( r ≥ 0.96, p < 0.001), while ACA showed weak to negligible correlations across all quadrants ( r ≤ 0.32). Bland–Altman analysis revealed small mean differences and narrow 95% limits of agreement (LoA) for ACD and ACV but large differences and wide LoA for ACA. Conclusions Pentacam and CASIA 2 demonstrated strong correlation and excellent agreement for ACD and ACV measurements. However, due to the slight systematic bias observed in ACD and ACV, clinicians should exercise caution when interchanging these measurements. In contrast, significant differences and poor agreement were found for ACA across all four quadrants, indicating that these two devices are not interchangeable for angle assessment.
Li et al. (Thu,) studied this question.