What question did this study set out to answer?

This review aims to summarize the history, current applications, and future prospects of BRTO in treating gastric varices and portosystemic shunt syndrome.

April 3, 2026Interventional Radiology0 citationsOpen Access

BRTO: Past, Present, and Future Directions

AYAkira YamamotoOsaka Metropolitan University AJAtushi JogoItami City Hospital KKKen KageyamaOsaka Metropolitan University

Key Points

This review aims to summarize the history, current applications, and future prospects of BRTO in treating gastric varices and portosystemic shunt syndrome.
Described the technique of BRTO and its modifications.
Reviewed indications for BRTO in gastric varices and portosystemic shunt syndrome.
Summarized evidence of BRTO's efficacy and liver function improvement post-procedure.
BRTO shows high therapeutic efficacy against gastric varices.
Improvement in liver function was noted following BRTO treatment.
BRTO is gaining acceptance outside of Asia, particularly in the United States and Europe.

Abstract

Balloon-occluded retrograde transvenous obliteration (BRTO) has been developed in Japan as a treatment for gastric varices (GV). The technique has spread mainly around Asia, but is now gaining wider recognition in the United States and Europe. BRTO is characterized by high therapeutic efficacy against GV, and a recent study demonstrated that BRTO resulted in improved liver function after the procedure. In addition, BRTO is becoming an effective treatment for the recently proposed concept of "portosystemic shunt syndrome". In this review, we describe the indications, methods, and modifications of BRTO, and also discuss the indications and current status of BRTO for portosystemic shunt syndrome.

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Yamamoto et al. (Tue,) studied this question.

synapsesocial.com/papers/69cf5f005a333a821460dd92 https://doi.org/https://doi.org/10.22575/interventionalradiology.2022-0013

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