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April 4, 2026Revista Brasileira de Oftalmologia0 citationsOpen Access

Primary conjunctival amyloidosis mimicking Parinaud's syndrome

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JRJaqueline Fernandes RuizTATalita Gambogi AraújoTBThaís Cândida Borges

Key Points

  • To analyze a rare case of conjunctival amyloidosis that resembled Parinaud's syndrome.
  • Case report of a 60-year-old female
  • Observation of a unilateral lesion in the inferior bulbar conjunctiva
  • Description of lesion characteristics including size and color
  • Lesion presented as extensive nodular mass
  • Poorly defined borders noted
  • Clinical presentation mimicked symptoms of Parinaud's syndrome

Abstract

Amyloidosis is characterized by the extracellular deposition of amyloid protein fibrils in tissues, including the conjunctiva, due to their insolubility in proteolytic enzymes. Conjunctival amyloidosis, particularly involving the eyelid conjunctiva, is a rare clinical entity. We report the case of a 60-year-old Caucasian female who presented with a unilateral lesion in the inferior bulbar conjunctiva, extending to the entire inferior tarsal region and fornix. The lesion appeared as an extensive, elevated, pinkish-yellowish nodular mass with poorly defined borders. An ...

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Cite This Study

Ruiz et al. (2026) studied this question.

synapsesocial.com/papers/69d0af83659487ece0fa5705https://doi.org/10.37039/1982.8551.20260028
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