Intracranial Changes after Fetal Spina Bifida Repair by 2D and 3D Slice-to-Volume MRI Reconstruction: Implications for the Etiology of Hydrocephalus.

Key Points

• This research aims to investigate the impacts of fetal spina bifida repair on brain structures and the relationship to hydrocephalus.
• Utilized 2D and 3D slice-to-volume MRI reconstruction techniques.
• Assessed changes in hindbrain herniation and ventricular size post-surgery.
• Analyzed the independent occurrence of hindbrain reversal and ventricular enlargement.
• Reversal of hindbrain herniation and ventricular enlargement were observed independently.
• Suggests that hydrocephalus may not solely result from obstruction.
• 3D slice-to-volume reconstruction offered improved measurement reliability.