What question did this study set out to answer?

To investigate the association between body roundness index (BRI) and diffuse idiopathic skeletal hyperostosis (DISH) in elderly patients.

April 5, 2026Scientific Reports0 citationsOpen Access

Association between body roundness index and the prevalence of diffuse idiopathic skeletal hyperostosis in elderly patients: the Bunkyo health study

YSYuta SugawaraJuntendo University HNHidetoshi NojiriJuntendo University MNMasashi NagaoJuntendo University

Key Points

To investigate the association between body roundness index (BRI) and diffuse idiopathic skeletal hyperostosis (DISH) in elderly patients.
Cross-sectional analysis of baseline data from a prospective cohort study.
Population consisted of 1,258 elderly individuals aged 65-84 from Bunkyo-ku, Tokyo.
Anthropometric measurements and InBody assessments were conducted, along with blood sampling for metabolic markers.
Lateral thoracolumbar radiography was used to identify DISH in participants.
Multivariate analyses were performed to determine relationships between BRI, visceral fat, and DISH.
DISH was present in 194 participants, representing 15.4% of the population.
Higher BRI was associated with DISH, with an odds ratio of 1.5.
Visceral fat volume also demonstrated a positive association with DISH, with an odds ratio of 1.01.
No significant differences were found in bone metabolic markers between DISH and non-DISH participants.

Abstract

Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by calcification and ossification of soft tissues. Previous studies have explored its links with diabetes, obesity, and visceral fat accumulation; however, no study has specifically evaluated its relationship with body roundness index (BRI). This cross-sectional analysis used baseline data from a prospective cohort of Japanese residents to investigate the association between DISH and the BRI, visceral fat volume, insulin resistance, and bone metabolic markers in an elderly urban Japanese population. We included 1,258 participants (535 men and 723 women, aged 65–84 years) from Bunkyo-ku, Tokyo. All participants underwent anthropometric measurements, InBody assessment, lateral thoracolumbar radiography, and blood sampling for bone metabolic markers. BRI was calculated using height and waist circumference. Participants with and without DISH were compared for BRI, visceral fat volume, and bone metabolic markers. Multivariate analyses were conducted to assess independent associations with DISH. DISH was identified in 194 participants (15.4%). Multivariate analysis demonstrated that higher BRI and visceral fat volume were independently associated with DISH (odds ratios: 1.5 and 1.01, respectively). We concluded that higher BRI and visceral fat volume were significantly associated with DISH in this elderly Japanese population, whereas bone metabolic markers showed no significant differences.

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