The last session of the 2025 Second Joint Congress of the British Society of Toxicological Pathology (BSTP) and the European Society of Toxicologic Pathology (ESTP) held in Manchester (United Kingdom) reviewed current recommendations and best practices for carcinogenicity risk assessment. The session comprised an introductory lecture about new approaches for screening for carcinogenicity, a joint session presenting a regulatory perspective about the Weight of Evidence (WoE) assessment for agrochemicals and pharmaceuticals, followed by another joint session elaborating on the industry experience about WoE. In addition, 3 case examples were presented to illustrate the challenges of in vivo carcinogenicity assessment in rodents within the current paradigm.
Palazzi et al. (Sun,) studied this question.