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January 28, 2022EP Europace68 citations

Does isolation of the left atrial posterior wall using cryoballoon ablation improve clinical outcomes in patients with persistent atrial fibrillation? A prospective randomized controlled trial

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JAJinhee AhnDSDong Geum ShinSHSang Jin Han

Structured PICO

Does adjunctive left atrial posterior wall isolation using cryoballoon ablation improve clinical outcomes compared to PVI only in patients with persistent atrial fibrillation?

P
Population
Patients with persistent atrial fibrillation (PeAF)
I
Intervention
Adjunctive left atrial posterior wall isolation (PWI) using cryoballoon ablation (CBA)
C
Comparator
Pulmonary vein isolation (PVI) only
O
Outcome
Clinical outcomes

Adjunctive posterior wall isolation using cryoballoon ablation improves clinical outcomes without increasing complications compared to PVI alone in patients with persistent atrial fibrillation.

Abstract

Compared with PVI only, adjunctive PWI achieved exclusively by CBA resulted in better clinical outcomes without increasing complications in patients with PeAF.

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Cite This Study

Ahn et al. (2022) studied this question.

synapsesocial.com/papers/69d56dce75589c71d767d0c7https://doi.org/10.1093/europace/euac005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation2016 · 1,952 citations
  2. 2Characterization of Left Atrial Activation in the Intact Human Heart2003 · 289 citations
  3. 3Left Atrial Anatomy Revisited2012 · 369 citations
  4. 4Clinical outcomes of adjunctive posterior wall isolation in persistent atrial fibrillation: A meta‐analysis2020 · 50 citations
  5. 5Arrhythmogenic Implications of Fibroblast-Myocyte Interactions2012 · 160 citations