Investigation of HE4 expression concerning epithelial-mesenchymal transition (EMT) in cystic fibrosis epithelial cells

Key Points

• To investigate the relationship between HE4 expression and epithelial-mesenchymal transition (EMT) in cystic fibrosis epithelial cells.
• Analysis of HE4 expression levels
• Measurement of MMP9 levels
• Use of airway epithelial cells from cystic fibrosis patients
• HE4 expression decreases during the process of EMT
• MMP9 levels are upregulated in cystic fibrosis epithelial cells