What question did this study set out to answer?

This study aims to compare the effectiveness of OLIF and MIS-TLIF in improving outcomes for patients with two-level degenerative lumbar disease.

April 8, 2026Asian Spine Journal0 citationsOpen Access

Comparison of functional and radiographic outcomes between two-level oblique lumbar interbody fusion and minimally invasive transforaminal lumbar interbody fusion in degenerative lumbar disease: a retrospective study in Thailand

WLWorawat LimthongkulChulalongkorn University KJKittitouch JirakiatChulalongkorn University MTMaruay TanayavongChulalongkorn University

Key Points

This study aims to compare the effectiveness of OLIF and MIS-TLIF in improving outcomes for patients with two-level degenerative lumbar disease.
Conducted a retrospective analysis of patient records.
Evaluated functional outcomes including pain and disability.
Assessed radiographic parameters to measure correction.
Compared short-term effects of OLIF versus MIS-TLIF.
Both OLIF and MIS-TLIF significantly reduced pain and disability.
MIS-TLIF provided faster short-term relief of leg pain.
OLIF achieved better radiographic correction than MIS-TLIF.
Further large-scale studies are needed to confirm these findings.

Abstract

OLIF and MIS-TLIF effectively improved pain, disability, and radiographic parameters in two-level lumbar degenerative disease. MIS-TLIF offered faster short-term leg pain relief, whereas OLIF achieved superior radiographic correction. Larger prospective studies are required to validate these findings and inform surgical decision-making.

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