Exosome research in GBM has expanded rapidly, with growing global participation and clear shifts toward translationally oriented themes. Current hotspots concentrate on tumor microenvironment regulation, immunotherapy-related mechanisms, and exosome-based liquid biopsy and brain-targeted delivery strategies. This knowledge mapping clarifies the field's intellectual structure and emerging frontiers, and may help guide future mechanistic studies and clinical translation of exosome-focused approaches in neuro-oncology.
Li et al. (Mon,) studied this question.