What question did this study set out to answer?

To investigate the relationship between genetic factors and the progression of asymmetric hearing loss in children.

April 8, 2026Clinical and Experimental Otorhinolaryngology0 citationsOpen Access

Genetic landscapes and audiological trajectories in pediatric asymmetric hearing loss and interaural asymmetry

SHSang-Yoon HanHanyang University MKMyeong Sin KangSeoul National University Hospital SJSung Ho JungGyeongsang National University

Key Points

To investigate the relationship between genetic factors and the progression of asymmetric hearing loss in children.
Analysis of genetically diagnosed pediatric cases of asymmetric hearing loss
Assessment of hearing deterioration rates particularly related to SLC26A4
Evaluation of the implications for rehabilitation planning based on genetic findings
SLC26A4-related cases show a higher rate of progression to cochlear implant than other associated genes
Findings indicate significant better-ear deterioration in these cases
Support for etiology-based prognostication and personalized rehabilitation strategies

Abstract

Genetically diagnosed cases show progressive better-ear deterioration. This is particularly evident in SLC26A4-related DFNB4, which has a higher rate of progression to CI than other AHL/IA-associated genes. These findings support etiology-based prognostication and individualized rehabilitation planning.

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Cite This Study

Han et al. (Mon,) studied this question.

synapsesocial.com/papers/69d5f13674eaea4b11a7ac8b https://doi.org/https://doi.org/10.21053/ceo.2026-00021

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