Is type 2 diabetes mellitus associated with altered heart rate variability?
Type 2 diabetes mellitus is associated with decreased heart rate variability, reflecting reduced sympathetic and parasympathetic activity likely due to cardiac autonomic neuropathy.
T2DM was associated with an overall decrease in the HRV of T2DM patients. Both sympathetic and parasympathetic activity were decreased, which can be explained by the deleterious effects of altered glucose metabolism on HRV, leading to cardiac autonomic neuropathy.
Benichou et al. (2018) studied this question.