Does 68Ga-FAPI PET imaging allow in vivo visualization of fibroblast activation and correlate with structural remodeling after acute myocardial infarction?
68Ga-FAPI PET is a promising imaging modality for the early in vivo visualization of fibroblast activation and structural remodeling after acute myocardial infarction.
This analysis demonstrates in vivo visualization of fibroblast activation after AMI. The uptake area showed a very good agreement with the affected coronary territory. A strong correlation of the de novo established parameter FAV with left ventricular function and peak creatine kinase was observed. This imaging modality may provide important insights into mechanisms of structural remodeling after AMI at an early stage.
Kessler et al. (2021) studied this question.
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