June 11, 2021Clinical Nuclear Medicine

Visualization of Fibroblast Activation After Myocardial Infarction Using 68Ga-FAPI PET

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Why the study?

Does 68Ga-FAPI PET imaging allow in vivo visualization of fibroblast activation and correlate with structural remodeling after acute myocardial infarction?

Population

Patients after AMI

Comparison

68Ga-FAPI PET imaging

Authors

LKLukas KesslerCardiac Imaging JKJana KupusovićElectrophysiology JFJustin FerdinandusUniversity of Cologne

Discussion

Member takes

Implication

May support post-MI fibroblast visualization; hypothesis-generating and requires prospective validation before clinical use.

Structured PICO

Does 68Ga-FAPI PET imaging allow in vivo visualization of fibroblast activation and correlate with structural remodeling after acute myocardial infarction?

Population

Subjects after acute myocardial infarction (AMI)

Intervention

68Ga-FAPI PET imaging

Outcome

In vivo visualization of fibroblast activation (uptake area agreement with affected coronary territory and correlation of FAV with left ventricular function and peak creatine kinase)surrogate

68Ga-FAPI PET is a promising imaging modality for the early in vivo visualization of fibroblast activation and structural remodeling after acute myocardial infarction.

Cite This Study

Kessler et al. (2021) studied this question.

synapsesocial.com/papers/69d80a5ef39344339dd1903d https://doi.org/10.1097/rlu.0000000000003745

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Visualization of Fibroblast Activation After Myocardial Infarction Using 68Ga-FAPI PET

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Visualization of Fibroblast Activation After Myocardial Infarction Using 68Ga-FAPI PET

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider